Toxic Impact of Nuvan (DDVP) on Tissues of Common Carp Channa punctatus (Bloch.)

Nuvan (DDVP) is a member of organophosphorus compounds. It is extremely toxic to insects and is widely used as insecticides. Nuvan has been taken for the acute toxicity to a fresh water fish Channa punctatus LC50 value calculated for the acute toxicity, which were 0.024 ml/L. Histopathological study of kidney and liver after 24hr, 48hr, 72hr and 96hr exposure to acute toxicity of Nuvan. Treatment with nuvan resulted in hypertrophy of hepatic cells, nacrosis and connective tissue damage in liver. Kidney showed shrinkage in glomerular network and desquamation of tubular cells. The aim of this study is to show the alteration in histopathological changes in liver and kidney and get the real picture of toxicological effect of organophosphate pesticide Nuvan, and correlated to know about the adverse consequence of environmental toxicant on human health. The study is very important from histopathological point of view. Keywords—Nuvan, Channa punctatus, kidney, liver.